A Randomized Trial Comparing Clinical Outcomes Of Two Hydrophobic Acrylic 1-Piece Intraocular Lenses

Published 2023 - 41st Congress of the ESCRS

Reference: PO0292 | DOI: 10.82333/60kq-d454

Authors: Shinichiro Nakano* ¹ , Hiroshi Sasaki ² , Atsushi Arimoto ³ , Tetsuro Oshika ⁴

¹Ophthalmology,Rygasaki Saiseikai Hospital,Ryugasaki,Japan, ²Ophthalmology,Kanazawa Medical University,Kanazawa,Japan, ³Ophthalmology,Anamizu General Hospital,Anamizu,Japan, ⁴Ophthalmology,University of Tsukuba,Tsukuba,Japan

To compare clinical results of two hydrophobic acrylic 1-piece intraocular lenses (IOLs), Clareon® and AcrySof IQ® IOL (Alcon, USA).

Ryugasaki Saiseikai hospital, Ibaraki, Japan

Kanazawa Medical University, Kanazawa, Japan

Anamizu General Hospital, Anamizu, Japan

Patients who were scheduled for bilateral cataract surgery and met all inclusion and exclusion criteria were randomized to receive Clareon in one eye and AcrySof IQ in the contralateral eye. Anterior chamber depth (ACD), corrected distance visual acuity (CDVA), and subjective and objective refractive error were measured at 1 day, 1 week, 1 month, 3 months, and 6 months postoperatively.

A total of 64 eyes of 32 cases were enrolled. ACD at 6 months was 4.26 ± 0.30 mm for Clareon and 4.23 ± 0.30 mm for AcySof IQ, with no statistical difference between the two IOLs (P= 0.052). The shifts from 1 day 1 to 6 months after surgery in ACD, CDVA logMAR, subjective and objective refractive error -0.10 ± 0.13 mm vs -0.13 ± 0.15 mm, -0.06 ± 0.08 vs -0.05 ± 0.10, 0.19 ± 0.83 D vs 0.04 ± 0.73 D, and 0.23 ± 0.92 D vs 0.09 ± 0.80 D in the Clareon and AcrySof IQ groups, respectively. None of these differences between two IOLs were statistically significant (P=0.25, 0.27, 0.08 and 0.17 respectively).

There were no statistical differences in ACD, CDVA, subjective, and objective refractive error between Clareon and AcrySof IQ IOLs. Both IOLs provided equivalent refraction stability and visual acuity outcomes.