Optical Coherence Tomography Used For Objective Quantification Of Glistening In Implanted Intraocular Lenses: Proposal For A New Classification And Grading System
Published 2023 - 41st Congress of the ESCRS
Reference: FP31.12 | Type: Free paper | DOI: 10.82333/bzfz-6444
Authors: María Teresa Serrano González-Peramato* 1 , José Ignacio Fernández-Vigo 2 , Bárbara Burgos-Blasco 2 , Ana Macarro-Merino 3 , Inés Sánchez-Guillén 1 , José Ángel Fernández-Vigo 4
1Hospital Universitario Badajoz,Badajoz,Spain, 2Hospital Clínico San Carlos,Madrid,Spain, 3Centro Internacional de Oftalmología Avanzada,Madrid,Spain, 4Centro Internacional de Oftalmología Avanzada,Badajoz,Spain
Purpose
To present a new classification of the glistening in intraocular lenses (IOL) using swept-source optical coherence tomography (SS-OCT) in order to identify a manageable, impartial and reproducible method to quantify its presence and severity
Setting
Cross-sectional study on 150 eyes of 150 patients who had undergone cataract surgery between 2 and 12 years before the exam and attended for a routine examination. After pupil dilatation, patients were examined by SS-OCT.
Methods
The degree of glistening or hyperreflective loci (HRF) in the central area of the IOL was classified into 4 groups: 0 (≤ 5 HRF), 1 (6-15 HRF), 2 (16-30 HRF) and 3 (> 30 HRF). Intra and interobserver reproducibility (intraclass correlation coefficient, ICC) and association between horizontal and vertical scans were also calculated and evaluated.
Results
Glistening was found in 42.7% of the patients. The average number of HRF was 10.4 ± 26.2 (range 0 to 239). The grade of glistening observed was 0 in 63.3% of patients, 1 in 20%, 2 in 6.7% and 3 in 10% of them. Intra and interobserver reproducibility was found to be very high in both absolute quantification of glistening (ICC ≥ 0.994) and severity scale (ICC ≥ 0.967). An excellent correlation between the results achieved by horizontal and vertical scans was found as well (R ≥ 0.834; p < 0.001).
Conclusions
SS-OCT is a useful tool for identification, quantification and classification of IOL glistening. This method could provide relevant information in order to study glistening in IOLs in a manageable, objective and reproducible way.