Patient Reported Outcomes Assessed Using The Near Activity Visual Questionnaire Of Presbyopic Subjects After Laser Scleral Microporation

To assess Patient Reported Outcome Measures (PROMs) of visual quality for activities of daily living (ADL’s) and quality of life resulting from the recovery of Dynamic Range of Focus (DroF) up to 24 months following Laser Scleral Microporation (LSM) therapy in presbyopic eyes. 

Asian Eye Institute, Philippines  

This prospective pilot clinical study enrolled 100 eyes of 50 presbyopic patients (mean age, 52.6 ± 4.0y) with DCNVA at 40cm ≥20/50; UDVA 20/40 or better, and free of ocular anomalies and requiring a reading add ≥ +1.5D. All subjects underwent LSM therapy to treat emmetropic presbyopia. The Near Activity Visual Questionnaire (NAVQ), a standardized questionnaire developed using PRO FDA guidance, was used to measure near vision function before and after the LSM therapy at baseline, and post procedure at 1 week, 1 month, 3, 6,12, 18 and 24 months. 

Data analysis showed at 24 months after LSM, Rasch Scores dropped significantly from 65.3 at baseline to 38.4 at 24 months (p < 0.001) This indicates a statistically significant improvement of improvement in the ability to perform near vision activities at 1 week after LSM and continuing to at least 24 months. PROMs also demonstrated an improvement in quality of life, with 75% of the patients reporting moderate to complete satisfaction with their near vision at 24 months.

The NAVQ revealed the burden of near work with presbyopia on quality of life and demonstrated the impact of LSM on performing ADLs requiring quality near vision. NAVQ assessments  indicated high patient satisfaction with the LSM therapy for treating presbyopia.