Myopic Shift In Automated Refraction Following Implantation Of Chromatic Aberration-Correcting Multifocal Intraocular Lens

To compare automated refraction and manifest refraction after implantation of multifocal IOLs with chromatic aberration-correction (DFR00V) and multifocal IOLs without chromatic aberration-correction (ZMB00 and POD F).

Omiya Nanasato Eye Institute, Saitama, Japan

A retrospective comparative study enrolling 282 eyes undergoing cataract surgery with implantation of multifocal IOLs (DFR00V group 128 eyes, ZMB00 group 92 eyes, POD F group 62 eyes) was performed. Keratometry was measured preoperatively. Spherical equivalent of automated refraction (TONOREF Ⅱ, NIDEK), manifest refraction and best corrected distance visual acuity were evaluated 3 months postoperatively.

The automated refraction (AR) of all groups showed a myopic shift compared to manifest refraction (MR). The amount of myopic shift (MR-AR), AR, MR were [0.63D, -0.94D, -0.32D], [0.28D, -0.24D, +0.04D], and [0.31D, -0.20D, +0.13D], in DFR00V group, ZMB00 group, and POD F group, respectively. The automated refraction of DFR00V group was significantly more myopic compared to all other groups (Turkey-Kramer, p<0.05). The amount of myopic shift in DFR00V group statistically correlated with axial length and IOL power (Pearson's correlation coefficient, p<0.05).

Automated refraction showed significant myopic shift in the DFR00V group, which may be due to the fact that autorefractors use near-infrared light for measurements, which may be influenced by chromatic aberration-correction. Thus, manifest refraction measurement after implantation of DFR00V should be performed carefully in order to compensate for myopic shift by automated refraction.