Paired Data Study On Corneal Epithelial Remodeling After Smile And Fs-Lasik Surgery In Myopia Patients Over 40 Years Old

To analyze the characteristics of corneal epithelial thickness changes in the early stage after SMILE and FS-LASIK surgery respectively in the eyes of the same myopia patient over 40 years old by using anterior segment OCT.  

CIRRUS HD-OCT(ZEISS)

A total of 20 myopia patients (40 eyes), aged (45.8±4.29) years, who underwent SMILE surgery in the dominant eye and FS-LASIK surgery in the non-dominant eye were collected. The corneal epithelial thickness of patients was measured using Zeiss anterior segment OCT before surgery, 1 week, 1 month and 3 months after surgery, respectively.

 At 1 month after operation: the central cornea of SMILE group was 0~2 and 2-5mm (inferior-nasal, inferior, temporal, inferior-temporal and temporal) thicker than those preoperative. In the FS-LASIK group, the corneal center 0~2, 2~5, and 6-7mm (nasal, inferior, inferior-temporal and temporal) areas were thicker than those preoperative (P<0.05). At 3 month after operation: the central corneal areas of 0-2 , 2-5  and 6-7 mm (nasal, inferior-nasal, inferior, superior-temporal, temporal) in the SMILE group were thicker than those preoperative(P<0.05); the central corneal areas of 0-2 , 2-5 , and 6-7 mm (superior-nasal, inferior-nasal, inferior, inferior-temporal, temporal) in the FS-LASIK group were thicker than those preoperative(P<0.05).

After SMILE and FS-LASIK surgery on both eyes of the same patient, corneal epithelial thickening of different degrees occurred in the early stage, and FS-LASIK surgery was more obvious, with longer duration and stronger variability. The potential influence of the characteristics of corneal epithelial remodeling on refractive stability after surgery needs further study, which may provide basis for the selection of preoperative surgery.