Prevalence Of Dry Eye Disease Among Individuals Scheduled For Cataract Surgery In A Norwegian Cataract Clinic
Published 2023 - 41st Congress of the ESCRS
Reference: FP12.12 | Type: Free paper | DOI: 10.82333/5c9g-jf10
Authors: Per Graae Jensen* 1 , Morten Gundersen 1 , Christian Nilsen 1 , Rick Potvin 2 , Kjell Gunnar Gundersen 1 , Parisa Gazerani 3 , Xiangjun Chen 4 , Tor Paaske Utheim 5 , Øygunn A. Utheim 6
1Eye,Ifocus eye clinic,Haugesund,Norway, 2Eye,Science in vision,Bend,United States, 3Faculty of Health Sciences,Oslo Metropolitan University,Oslo,Norway, 4Department of Medical Biochemistry,Oslo University Hospital,Oslo,Norway;Department of Ophthalmology,sørlandet Sykehus,Arendal,Norway;Department of Ophthalmology,Vestre Viken Hospital,Oslo,Norway, 5Faculty of Health Sciences,Oslo Metropolitan University,Oslo,Norway;Department of Medical Biochemistry,Oslo University Hospital,Oslo,Norway;Department of Ophthalmology,Oslo University Hospital,Oslo,Norway;Eye,The Norwegian Dry Eye Clinic,Oslo,Norway, 6Department of Medical Biochemistry,Oslo University Hospital,Oslo,Norway;Department of Ophthalmology,Oslo University Hospital,Oslo,Norway;Eye,The Norwegian Dry Eye Clinic,Oslo,Norway
Purpose
To determine the prevalence of dry eye disease (DED) in patients presenting for cataract surgery at one site in Norway with validated subjective and objective testing.
Setting
Single cataract clinic in Norway
Methods
218 patients presenting for cataract surgery were screened for DED in one randomly selected eye and questioned regarding risk factors. Eyes were categorized as having DED based on the DEWS II criteria with a positive symptom score from the Ocular Surface Disease Index (OSDI) questionnaire, and the presence of any of the three signs: elevated tear osmolarity or a large interocular difference, corneal fluorescein staining (CSF) and non-invasive tear film breakup (NIKBUT).
Results
The prevalence of DED was 55.5% according to the DEWS II criteria. 66.5% had abnormal osmolarity, 29.8% had shortened NIKBUT and 19.7% exhibited CFS ≥2. 57% had Schirmer 1 ≤ 10 mm/5 min, and 81.1% had a meiboscore of ≥1. 71.2% of subjects were DED-positive using the OSDI questionnaire and 69.3% using SPEED. Logistic regression analysis showed that higher age correlated with a lower OSDI symptom score, reduced corneal sensibility and increased meibomian gland atrophy. Female sex was associated with higher odds of having DED, abnormal NIKBUT and abnormal CFS. Objective DED tests did not correlate with OSDI scores when assessed with Spearman`s rank analysis.
Conclusions
The prevalence of DED in an elderly Norwegian population scheduled for cataract surgery is high and associated with female sex. Both aqueous deficient dry eye and meibomian gland dysfunction are common. The correlation between signs and symptoms of DED is weak.