Capsular Irrigation With Anti-Vegf In Pediatric Cataract Surgery

To determine the safety and efficacy of irrigation of the capsular bag with anti-VEGF during pediatric cataract surgery

Department of Ophthalmology, Sohag university Hospital, Sohag Faculty of Medicine, Sohag University, Sohag, Egypt.

15 eyes of 9 children (Age 18-42 months, average 26 months) with isolated congenital cataract underwent irrigation/aspiration with primary PCIOL implantation. Principles included anterior CCC, I/A, irrigation with ranibizumab for two minutes, BSS irrigation, post. CCC, 3-piece IOL inserted in the ciliary sulcus with optic capture.

Control group: 30 eyes of 18 children with isolated congenital cataract underwent the same procedure without use of ranibizumab.

Outcome measures: at 6 months postoperative

Vision, visual axis opacification, postoperative complications.

Vision (preferential looking): Study group ( 12 eyes good vision, 3 eyes fair vision), control group (25 eyes good vision, 5 eyes fair vision), no statistically significant difference.

Postoperative complications: 2ry glaucoma (2 eyes of study group, 3 eyes of control group), early postoperative iritis (1 eye in both groups), no statistically significant difference.

Visual axis opacification and PCO: 4 eyes in study group and 5 eyes in control group, no statistically significant difference.

Irrigation of the capsular bag with ranibizumab during congenital cataract surgery is a safe technique. However, it  showed no additional benefits in preventing PCO. Further studies on large sample are recommended.