ESCRS - PO315 - Corneal Biomechanical Properties In Early Keratoconus, High Astigmatism And Normal

Corneal Biomechanical Properties In Early Keratoconus, High Astigmatism And Normal

Published 2022 - 40th Congress of the ESCRS

Reference: PO315 | Type: ESCRS 2022 - Posters | DOI: 10.82333/yk60-8v90

Authors: Norsyariza Razak 1 , Wan Haslina Wan Abdul Halim* 1

1ophthalmology,national university of Malaysia,kuala lumpur,Malaysia

Purpose

To assess corneal biomechanical parameters in early keratoconus, high astigmatism and normal subject with normal corneal topography finding

Setting

Ophthalmology Clinic, Hospital Canselor Tuanku Muhriz, National University of Malaysia, Kuala Lumpur, Malaysia

Methods

It’s an observational study consist of total 66 eyes. 22 eyes of subjects diagnosed with early keratoconus (TKC 1-2) using Pentacam HR, 22 eyes of high astigmatisms patients (>2.0DC and < 6.0DC) and 22 eyes of normal healthy subjects with normal corneal topography finding. All subjects have undergone corneal biomechanical assessment using Corvis ST. Dynamic corneal response (DCR) parameters A1T, A2T, A1L, A2L, A1V, A2V, HCT, HCPD, HCR and HCDA were recorded. Stiffness parameter at A1(SP A1), Ambrosio relational thickness (ARTh), Corvis Biomechanical index (CBI), DA ratio max and integrated radius (IR) were also recorded and compared.

Results

Most corneal biomechanics parameters (A1T, A1L, A2L, A1L, A2V, HCPD, HCDA, SP A1, ARTh, DA, IR and CBI) were significantly different when compared between early keratoconus group to high astigmatism group and normal group (p<0.05). Only A2L, A1V, A2V, HCR and ARTh were found to be significantly different between astigmatism group and normal group (p<0.05). Early keratoconus has significantly reduced SP A1 compared to high astigmatisms and normal subjects.

Conclusions

Corneal biomechanics assessment is useful for detecting keratoconus at the earliest stage. It can also distinguish between early keratoconus and high astigmatism when both corneal topographies are normal. Decreased corneal stiffness occurs in the early stages of keratoconus, while evidence on corneal topography may still not be visible.