Artificial Iris And Intraocular Lens Complex: Outcomes And Surgical Techniques

Published 2022 - 40th Congress of the ESCRS

Reference: FPS12.08 | Type: Free paper | DOI: 10.82333/05d6-cs63

Authors: Shakeel Qazi ¹ , Victoria Liu* ² , Vaitheeswaran Lalgudi ² , Bader Al-Qahtani ² , Saama Sabeti ³ , Darrell Lewis ¹ , Rishi Gupta ⁴ , Kashif Baig ⁵

¹Precision Cornea Centre,Ottawa,Canada, ²Department of Ophthalmology,University of Ottawa,Ottawa,Canada, ³Precision Cornea Centre,Ottawa,Canada;Department of Ophthalmology,University of Ottawa,Ottawa,Canada;Herzig Eye Institute,Ottawa,Canada, ⁴Department of Ophthalmology and Visual Sciences,Dalhousie University,Halifax,Canada, ⁵Precision Cornea Centre,Ottawa,Canada;Department of Ophthalmology,University of Ottawa,Ottawa,Canada;Herzig Eye Institute ,Ottawa,Canada

Purpose

To report the outcomes and describe the surgical technique for the largest case series of Reper artificial iris and intraocular lens (IOL) complex for treating aniridia and aphakia.

Setting

Precision Cornea Centre, Ottawa, ON, Canada

Methods

This is a retrospective case series including data from patients that underwent implantation of the Reper (Nizhny Novgorod) artificial iris and IOL complex. Clinical outcomes were assessed at the standard of care postoperative follow up visits at 1 day, 1 week, 1 month and 3 months. Key outcomes assessed included best-corrected visual acuity (BCVA), subjective glare and photophobia reduction, intraocular pressure, complications, and cosmesis.

Results

Eleven eyes (11 patients) were included in the study. The median UCDVA and BCDVA improved from 1.80 ± 0.59 and 1.30 ± 0.71 to a logMAR of 0.88 ± 0.65 (P = 0.01) and 0.50 ± 0.23 (P = 0.18), respectively. There were 4 cases of postoperative hypotony, 4 cases of intraocular pressure (IOP) elevation, 1 case of persistent corneal edema, 1 case of transient corneal edema, 1 microhyphema, 1 pigment dispersion syndrome, and 2 cases of exposed sutures. No eyes had signs of persistent intraocular inflammation. The majority of patients (n=10) reported an improvement in photophobia and glare.

Conclusions

The Reper artificial iris and IOL complex was effective at correcting aniridia and aphakia with a single device. Furthermore, it was effective at improving visual acuity, reducing glare and photophobia, and improving cosmesis in patients with aniridia and aphakia. In this case series, significant rates of complications were experienced, however, patients undergoing implantation had significant pre-existing ocular comorbidities and visual compromise.