Promising Therapy for radiation maculopathy
Intravitreal pharmacotherapy may moderate anatomic and visual effects of radiation-associated maculopathy


Sean Henahan
Published: Wednesday, January 11, 2017

Timothy Murray MD
Of most importance to the patients, at two months visual acuity had improved to 20/51, and at six months had improved to 20/32He described several cases where patients demonstrated dramatic improvement. One such case was a 76-year-old patient who had 20/400 BCVA at the beginning of the study. After receiving anti-VEGF treatment at six week intervals he improved to 20/30, with significant improvement also noted on OCT. Another patient, enrolled eight months post-brachytherapy, presented with both radiation maculopathy and optic neuropathy. After 66 weeks on the treat-and-extend protocol she also showed marked improvement on her OCT, with visual acuity improving from 20/400 to 20/30. “Ultimately, this interim data does suggest the potential for a large, multicentre randomised controlled clinical trial, and supports the recent shift within the ocular oncology community to the use of intravitreal pharmacotherapy in the management of radiation-related complications in uveal melanoma,” Dr Murray concluded. Timothy Murray: tmurray@murraymd.com
Latest Articles
Beyond the Numbers
Empowering patient participation fosters continuous innovation in cataract surgery.
Thinking Beyond the Surgery Room
Practice management workshop focuses on financial operations and AI business applications.
Aid Cuts Threaten Global Eye Care Progress
USAID closure leads retreat in development assistance.
Supplement: ESCRS Clinical Trends Series: Presbyopia
Nutrition and the Eye: A Recipe for Success
A look at the evidence for tasty ways of lowering risks and improving ocular health.
New Award to Encourage Research into Sustainable Practices
Sharing a Vision for the Future
ESCRS leaders update Trieste conference on ESCRS initiatives.
Extending Depth of Satisfaction
The ESCRS Eye Journal Club discuss a new study reviewing the causes and management of dissatisfaction after implantation of an EDOF IOL.
Conventional Versus Laser-Assisted Cataract Surgery
Evidence favours conventional technique in most cases.
AI Scribing and Telephone Management
Automating note-taking and call centres could boost practice efficiency.