Anti-VEGF therapy may revolutionize ROP treatment
A single intravitreal injection of an anti-VEGF agent in babies with retinopathy of prematurity
induces regression of pathological neovascularization and also promotes resumption of
physiological vascularization of the retina, Tim U Krohne MD of the University of Bonn Eye
Clinic told the World Society of Paediatric Ophthalmology & Strabismus. As such, it could
eliminate the need to ablate avascular retina tissue and has the potential to revolutionize ROP
treatment.
However, several issues must be addressed before anti-VEGF is adopted, Dr Krohne said. These
include establishing the smallest effective dose and assessing safety with particular attention to
systemic side effects. Injection sight is also an issue since premature infant eyes are very small.
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