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Choroidal thickness in Turkish children with anisometric amblyopia

Poster Details

First Author: E.Karaca TURKEY

Co Author(s):    H. Akcam   M. Çubuk   F. Uzun   E. Yüksel     

Abstract Details


To assess macular choroidal thickness (CT) in children with anisometropic amblyopia and to compare the measurements with that of fellow non-amblyopic eyes and age-sex matched controls.


Gazi University, Ankara, Turkey


Forty patients with anisometropic amblyopia and 40 age-sex matched controls were evaulated in this study. Eyes were classified into three groups as follow; group 1, amblyopic eyes (n=40); group 2, fellow non-amblyopic eyes (n=40); and group 3, healthy eyes (n=40). All subjects underwent complete ophthalmic examination and macular choroidal thickness measurements by enhanced depth imaging method of the Spectralis optical coherence tomography system. CT was measured at the fovea and at 1,000-μm intervals from the foveal center in both temporal and nasal directions. The statistical assessment was performed with the assistance of one way analysis of variance (ANOVA) and Pearson’s correlation test.


The mean subfoveal CT was 389.35, 349.07 and 315.8 μm in the amblyopic, fellow and healthy eyes, respectively. CT was greatest in subfoveal and lowest in nasal regions for all groups. Both amblyopic and fellow non-amblyopic eyes were more hyperopic than healthy eyes. While the subfoveal and nasal CT in group 1 and 2 were significantly thicker than healthy eyes; the temporal CT only in group 1 was significantly thicker than healthy eyes. There was a significant positive correlation between the CT of the subfoveal, nasal and temporal regions and the refraction (r=0.432 P=0.001; r=0.324 P=0.001; r=0.215 P=0.01 respectively).


The macular choroidal thickness not only in amblyopic eyes but also in non-amblyopic fellow eyes are significantly thicker than the healthy subjects. The thick choroid in amblyopic and non-amblyopic fellow eyes may indicate bilateral delay of emmetropization, which probably means amblyopia, affecting the visual feedback of both eyes.

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