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The preoperative use of antibiotics in cataract surgery: yes

Poster Details

First Author: M.Trenkic Bozinovic SERBIA

Co Author(s):    D. Veselinovic   J. Jocic Djordjevic   B. Tomasevic   M. Petrovic   S. Novak   M. Radenkovic

Abstract Details


The aim of our study was the microbiological analysis of the bacterial flora of the conjunctiva, their preoperative eradication in terms of prophylaxis of endophthalmitis following cataract surgery and determine the effectiveness of ofloxacin 0.3 % in bacteria reduction.


Department of Ophthalmology, University Medical Center Nis, Serbia


The study included 120 patients with senile cataract. A control group of 60 patients did not received antibiotics preoperatively. A second group of 60 patients was treated topically with ofloxacin 0.3%, four times a day for four days prior to surgery, and four times for two hours prior to surgery. Examination of the conjunctival flora was carried out using standard microbiological procedures. The conjunctival swabs were collected at the time of the selection for surgery ( I swab), four days before surgery ( II swab) and immediately before the operation ( III swab).


In the control group of patients, the first and second conjunctival swabs were positive in nine and negative in 51 patients. The third swab findings did not changed (no statistically significant difference, χ2 test, p more 0,05). In the therapy group of patients, the first and second swab were positive in six cases and negative in 54 patients. The third sample was sterile in all 60 patients (statistically significant difference, χ2 test, p less 0,05). The most common findings were Staphylococcus aureus (6 swabs) and Staphylococcus epidermidis (5), Enterobacter spp. (2), Proteus mirabilis (1) and Pseudomonas aeruginosa (1).


Topical ofloxacin 0.3 % for four days prior to surgery, and four times in two hours before the operation is effective in the elimination of the bacterial flora of the conjunctiva and the sterility is achieved in all cases. FINANCIAL INTEREST: NONE.

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