ESCRS - Virtual Refractive Surgery for the Prevention Of Negative Dysphotopsia (“vRESPOND”) study

Virtual Refractive Surgery for the Prevention Of Negative Dysphotopsia (“vRESPOND”) study

vRESPOND Project Summary

The overall goal of the vRESPOND study is to provide a clinically feasible and cost-effective

Method to manage negative dysphotopsia (ND). We aim to use MRI-based patient-specific eye-models to uncover the underlying optical origin of ND through ray-tracing simulations. We subsequently aim to develop a Virtual Refractive Surgery application for the prevention and treatment of ND.

In terms of specific research aims:

  • comprehensive clinical evaluation will be made of 60 ND patients and 60 pseudophakic controls both in terms of objective ophthalmic measurements and standardized questionnaires.
  • Based on these data, ray-tracing analyses will be performed using the patient-specific, MRI-based, eye-models to:
    1. elucidate the mechanism for ND
    2. determine the key aspects of IOL design to prevent ND
    3. develop the Virtual Refractive Surgery model to preoperatively select high-risk patients and guide to the optimal IOL-type to prevent ND for these high-risk patients.

Project leader

Dr. Jan Willem Beenakker

Leiden, The Netherlands

Amount awarded by ESCRS

€650,195

Status

PROJECT COMPLETED

vRESPOND Resources

Increased peripheral spherical aberrations are present in patients with negative dysphotopsia
Video
Increased peripheral spherical aberrations are present in patients with negative dysphotopsia
Negative Dysphtopsias
Video
Negative Dysphtopsias
Peripheral aberrations in negative dysphotopsia
Video
Peripheral aberrations in negative dysphotopsia
EyeContact interview: The vRESPOND study; an interview with the project leader
Video
EyeContact interview: The vRESPOND study; an interview with the project leader
Uncovering the origin of negative dysphotopsias with MRI: the ESCRS vRESPOND study
Video
Uncovering the origin of negative dysphotopsias with MRI: the ESCRS vRESPOND study
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Past/Present ESCRS Research Projects