Information Registration Programme Overview Satellite Education Programme Virtual Exhibitor Listing


All ePoster presentations will be available to view anytime throughout the Meeting in an Online Library

Search Abstracts by author or title


Rapidly progressing ocular surface squamous neoplasia and topical alpha-2-beta Interferon: does the size matter?

Poster Details

First Author: P. Cid-Bertomeu SPAIN

Co Author(s):    V. Huerva Escanilla   M. Vilatella Ortiz   M. Sancho Romero   M. Dominguez Bernaus           

Abstract Details


To report a case of a large and bilobate vision-threatening ocular surface squamous neoplasia (OSSN) treated conservatively with topical alpha-2-beta interferon (IFN a-2b).


Department of Ophthalmology. Arnau de Vilanova University Hospital. University of Lleida. Lleida, Spain.


Case Report. Images and follow-up took place between August and December of 2020. Informed consent was obtained from the patient.


A 58-year-old man presented with an epithelial nodular and bilobed large conjunctival tumour with corneal invasion in his right eye. Rapid progression was determined as he explained a clinical onset of two months. Anterior segment HD-OCT revealed a thickened hyperreflective epithelium and an abrupt transition between normal and abnormal epithelium. Incisional biopsy was performed and histopathologic examination informed a squamous carcinoma with subepithelial infiltration. He was treated with topical IFN a-2b 4 times daily during 12 weeks. Reduction of the size of the tumour was observed during follow-up and total resolution was accomplished with no visible lesions since 6th week.


Topical IFN a-2b has demonstrated to be and effective treatment of OSSN even in those cases with a large size tumour were surgical management seems to be the only option. Our case aims to highlight the excellent results of this therapy with a large and rapidly progressive squamous conjunctival neoplasia and its good safety profile with no ocular side effects reported.

Financial Disclosure:


Back to Poster listing