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IBERIA Biobank: causes of explantation of IOLs by bilensectomy
First Author: J. Alio SPAIN
Co Author(s): K. Mena A. Rodriguez J. Murta R. Barraquer
The main objective of this work is to present the causes of explants associated with the phakic and pseudophakic lenses explanted by the technique of bilensectomy, coming from the IBERIA Biobank of ophthalmic explants until 2020.
1. Division of Ophthalmology, Miguel Hernandez University, Alicante, Spain. 2. Miranza ﾖ VISSUM Alicante, Alicante, Spain. 3. Department of Ophthalmology, Coimbra University, Coimbra, Portugal. 4. Barraquer Ophthalmology center, Barcelona, Spain. 5. Ocular Diopter Node, OFTARED - RETICS, Spain.
The explanted IOLs are stored in a fixation solution to preserve biological information. RETICS members collect the explanted material from the eye and the related data and send it to IBERIA Biobank to register and store it for future studies. The IBERIA Biobank's development and expansion are two of the milestones in the current RETIC project with reference number RD16/0008. This presentation aims to offer an interim report about the causes of IOL explantation in Spain at the present moment.
Nowadays, the IBERIA Biobank gathers a total of 1755 explanted samples prospectively. Of the total amount IOLs recorded, phakic (488) and pseudophakic (577) lenses. Focusing on the Phakic lenses, the main causes of explant by bilensectomy are: cataract (50,82%), endothelial damage (5,94%), lens opacity (3,89%), and low VA and IOL dislocation (2,46%), respectively. In Pseudophakic lenses, the main causes of explant are: IOL dislocation (27,73%), keratoplasty (20,28%), corneal damage (7,63%), IOL opacity (6,41%), neuroadaptive failure (5,72%), low VA (4,85%) and cataract (3,12%).
To increase patients' quality of life implanted with intraocular lenses, it is necessary to know the reasons for failure, leading to explantation. To accomplish this goal, it is essential to further carry out a multi-institutional collaborative work to deepen the causes of these biomedical devices' explants. The IBERIA Biobank is available for the scientific community. These data are available on request and with the agreement of the specific committee for research studies. All interested centers can contribute and broaden the Biobank by sending the explanted samples with the form.
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