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XENIA™ Lenticule for management of keratoconus or post-LASIK ectasia: one year results
First Author: B. Ilango UK
Co Author(s): L. Jiang
The management of keratoconus and post-LASIK ectasia can be challenging. Often these patients have poor unaided and aided vision; they are often spectacle & contact lens intolerance. We describe a form of SLAK using a XENIAﾙ Lenticule - a novel biocompatible corneal lenticule of highly purified corneal collagen fibres of porcine origin. One year results of the first 9 patients treated with this technique are presented.
All the patients were treated at Optimax Eye Clinics in England, UK. A single surgeon (1st author) treated all the nine patients. Patients were recruited following referral from other Eye Centres; all patients were counselled, explained all other options and informed consenting form completed
A total of 9 eyes of 9 patients have undergone the procedure. 6 eyes with keratoconus and 3 with post-LASIK ectasia.. A custom corneal stromal pocket of 100?m depth and 8.7mm diameter was created with a 3.7 mm access port using an Intralase femtosecond laser. A 120?m thick (initial 6 patients & 80 microns thick for last 3 patients), 7.2/8 mm diameter Gebauerﾙ lenticule was implanted into this stromal pocket though the 3.7 mm port. No sutures were used. Pre and post operative topography, pachymetry, intraocular pressures were recorded as well as aided, unaided and corrected vision.
Following implantation of the lenticule, average corneal thickness was increased from 401?m to 513?m. Average optical k readings were not statistically altered (51.4 D vs 51.5D). Anterior corneal astigmatism decreased from 7.4 D to 2.0D. Unaided vision improved from 1.74 LogMar to 1.54 LogMar.
The XENIA Implant - one year results seems to be very promising in stabilising keratoconic and post-lasik ectasia eyes. There is also no reliance on human tissue donors, solving the three main issues of current surgical management of these patients ﾖ rejection, shortage of donor material & possibility of COVID-19 transmission via the donor organs Both the 110 & 80 microns XENIA Implants seem to be equally effective. However, larger series study needs to be carried out to confirm
research is funded, fully or partially, by a company producing, developing or supplying the product or procedure presented
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