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Validation of defocus tolerance of novel aberration-neutral hydrophobic acrylic monofocal IOL

Poster Details

First Author: V.Kolesnitchenko USA

Co Author(s):    A. Pilon                    

Abstract Details


To assess the refractive efficacy, accuracy to target and tolerance to defocus of aberration-neutral, hydrophobic acrylic monofocal (MX60, Bausch & Lomb) intraocular lens (IOL) technology when used to correct aphakia following cataract extraction in adults


Multi-centered, clinical case series


A multi-center, multi-surgeon, retrospective case series involving 125 eyes of 125 adult subjects with age-related cataract amenable to treatment with standard cataract extraction. Visual outcomes at 6 months (120-180 days post-op) were analyzed to determine uncorrected distance visual acuity (UCDVA), manifest refraction spherical equivalency (MRSE), absolute aim error (AAE), and assessment of UCDVA relative to MRSE


Collected values revealed mean UCDVA of 0.126±0.19 logMAR, mean MRSE of 0.054±0.56 D and AAE of 0.401±0.33 D. Refractive accuracy to target SE was found to be 44.26% of subjects within ±0.25D, 70.49% within ±0.50D and 95.08% within ±1.00D. Comparative analysis of UCDVA to MRSE diverged from the assumed impact increasing residual myopic MRSE is anticipated to have on resultant UCDVA (1 line reduction in visual acuity per -0.25D of uncorrected MRSE). LogMAR values stratified by residual MRSE were -0.027 (0.00 to -0.25D), 0.069 (-0.25 to -0.50D), 0.151 (-0.50 to -0.75D) and 0.363 (-0.75 to 1.00D), respectfully


The aberration-neutral hydrophobic acrylic monofocal IOL evaluated demonstrated excellent refractive efficacy and accuracy in attaining refractive target. A unique feature that was validated during this study was this platform’s capacity to provide tolerance to defocus by allowing subjects to retain consistent UCDVA across a wide range of residual MRSE; a feature that may provide surgeon with more range of focus around their planned refractive target or a means to expand the range of monovision correction without sacrificing distance acuity

Financial Disclosure:

is employed by a for-profit company with an interest in the subject of the presentation

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