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Prospective clinical trial of unilateral or bilateral implantation of enlarged depth-of-focus intraocular lens in cataract patients with presbyopia

Poster Details

First Author: S.Choi SOUTH KOREA

Co Author(s):    H. Lee   C. Yoon   M. Kim              

Abstract Details


To investigate the clinical outcome of unilateral or bilateral implantation of the enlarged depth-of-focus intraocular lens (EDOF IOL, TecnisSymfony®) in cataract patients with presbyopia.


This prospective clinical trial included 20 eyes of 17 patients with cataract and presbyopia who received implantation of unilateral (n=14) or bilateral (n=3) EDOF IOL after phacoemulsification at Seoul National University Hospital by a single surgeon (MK Kim).


The patients underwent uneventful phacoemulsification and implantation of TecnisSymfony®. Mean absolute error (MAE) at 1 month was compared in SRK/T, Holladay2, Haigis, Hoffer Q, Barrett Universal II, and Hill-RBF formula. At postoperative 1, 4, and 12 weeks, logMAR visual acuity (logMARVA) at the distance (5m), intermediate (66cm), and near (40cm), and spherical equivalent (SE) in manifested refraction (MR) and automated refraction (AR) were measured. Wavefront aberration, contrast sensitivity test, and glare test were done at 12 weeks. The questionnaire was used to investigate glare, glasses dependency, and patient satisfaction at 12 weeks.


At 4 weeks, the logMARVA significantly improved to -0.02 at distance, 0.06 at intermediate, and 0.28 at near (p<0.05) and were maintained up to 3 months. SE was -0.88D on AR, and was significantly lower than the -0.34D measure by MR. The percentage of eyes within ± 0.5D of the target refraction was highest with Hoffer Q formula, and the MAE was lowest using Barrett Universal II formula. Only 7% of the patients required near glasses and 25% of the patients complained of blurred vision at 12 weeks. No patients reported bilateral imbalance due to unilateral surgery.


Unilateral or bilateral implantation of the EDOF IOL is effective in improving visual acuity without spectacle dependence or bilateral imbalance.

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