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Clinical-laboratory evaluation of the medicine efficacy based on metronidazole and tar in the treatment of demodectic blepharitis

Poster Details

First Author: I.Medvedev RUSSIA

Co Author(s):    N. Dergacheva                    

Abstract Details


To study the influence of the mono- and complex therapy by cream and shampoo «Demazol» on the dynamics of clinical and laboratory parameters (akarogramms) in patients with Demodex blepharitis.


Pirogov Russian National Research Medical University (RNRMU), Moscow, Russia


There were 45 patients (aged from 23 to 86 years) with Demodex blepharitis/blepharoconjunctivitis in the study. The akarogramms indicated the number of adult mites, larvae and eggs of parasites separately for each eye. Patients were divided into two groups: group I- monotherapy(cream), group II - complex therapy (cream and shampoo). For the study, patients took epilated 16 eyelashes and microscopy. The cream was applied on the eyelids 2 times a day, and before this pretreatment-alcohol eucalyptus tincture (both groups). Additionally, shampoo was applied on facial and ears skin (group ll). The course of treatment was 45 days.


In both group, the cream and shampoo «Demazol» had eliminated all forms of the mite Demodex — adults, larvae and eggs of parasites after 45 days of application. The number of mites after the course was significantly reduced in both groups: 5 and 18.6 times (by the number of adults); 3 and 7.6 times (the number of larvae), 7 and 5,5 times (the number of parasite eggs). Reduction the number of ticks was noted in general by 95% of patients; full or substantial reduction by 79,8% in group l and 94,6% in group ll, proving the specific efficacy complex therapy.


The cream and shampoo ( complex therapy) "Demazol" is an effective method of treatment Demodex blepharitis and can be recommended for a complex therapy of this conditions.

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