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Correlations between macular vessel density and macular thickness in early stage primary open-angle glaucoma

Poster Details

First Author: A.Usman BELARUS

Co Author(s):    L. Marchenko   T. Katchan                 

Abstract Details


To assess the correlations between Macular vessel Density and inner Macular Thickness in patients with early stage of Primary Open-angle Glaucoma (POAG) using the optovue optical coherence tomography Angiography (OCT-Angio).


3rd Minsk City Clinical Hospital, Department of Ophthalmology, Belarusian State Medical University, Minsk, Belarus


In a cross-sectional study, 60 eyes of 43 patients with early POAG, 44 eyes of 27 glaucoma suspects and 30 eyes of 15 control subjects with a respective mean age of 65.47 ± 9.59, 56.53 ± 9.31 and 51.65 ± 4.16, underwent vessel density and retina thickness measurements in the 6 x 6 mm macular zone using OCT-Angio, RTVue-100. Parameters evaluated were superficial vessel density and inner macular thicknesses of the total, superior, inferior, nasal and temporal quadrants of the macular. A Spearman Rank Order Correlations was use to compare between the vessel density and the structural changes.


The early POAG patients had significant decrease in all the parameters of both the macular vessel densities and inner macular thicknesses as compared to the control group (p<0.05) but not compared to the glaucoma suspect group (p>0.05). Positive correlations were identified between the macular vessel densities and the various inner macular thickness in all the parameters analyzed. However, none was statistically significantly correlated (p>0.05). The highest correlation was noticed between temporal inner Macular Thickness and vessel densities in the inferior and nasal macular quadrants (R= 0.35).


In early POAG, Non-statistically significant positive correlations were identified between the superficial macular vessel density and inner macular thickness using the OCT-Angio RTVue-100.

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