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Goniotomy with trabecular meshwork excision using the Kahook dual blade in severe and refractory glaucoma: six month outcomes

Poster Details

First Author: K.Mansouri SWITZERLAND

Co Author(s):    L. Salinas   A. Chaudhary   S. Dorairaj   J. Berdahl   G. Lazcano-Gomez   L. Seibold     

Abstract Details


To describe short-term efficacy and safety of goniotomy with trabecular meshwork excision using the Kahook Dual Blade (New World Medical Inc., Rancho Cucamonga, CA) in patients with severe or refractory glaucoma.


Retrospective multicentric case series of 53 eyes with severe or refractory glaucoma as defined by ICD-10 conducted in the USA, Mexico and Switzerland.


Primary efficacy outcome was a 20% or more decrease in intraocular pressure (IOP) from baseline at 6 months. Secondary efficacy outcome measures were probability of achieving an intraocular pressure 16 or 18 mm Hg at 6 months and the mean IOP change from baseline at 6 months. Medication use required to obtain target intraocular pressure (IOP) at last follow-up and adverse effects were analyzed.


The proportion of eyes achieving an IOP reduction of more than 20% from baseline at 6 months was 57.7% (n = 30). Mean IOP decreased from 18.4 ± 6.1 mm Hg at baseline to 13.9 ± 3.5 mmHg at month 6 (23.9% reduction, P < 0.001). At 6 months, 51.9% and 40.4% achieved an IOP 16 or 18 mm Hg, respectively, and the mean number of glaucoma medications was reduced by 1.2 ± 1.3 (36.6%) compared to baseline (P <0.001). The most common adverse event was blood reflux (n = 29, 34.9%). No severe complications were reported.


Goniotomy with trabecular meshwork excision using the Kahook Dual Blade could be an alternative surgery for severe or refractory glaucoma, significantly reducing IOP and medication use at 6 months, with a low rate of complications.

Financial Disclosure:

receives consulting fees, retainer, or contract payments from a competing company

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