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Study to evaluate the effectiveness of high frequency deep sclerotomy (HFDS) in treatment of primary open-angle glaucoma (POAG)

Poster Details

First Author: Z.Khatib INDIA

Co Author(s):    V. Shetty   S. Haldipurkar   P. Sankhe              

Abstract Details


To compare the intraocular pressure (IOP), retinal nerve fibre layer (RNFL) thickness, visual field changes and dependency on antiglaucoma medications pre and post HFDS surgery in patients with POAG.


Laxmi Eye Institute, Navi Mumbai.


92 eyes of 71 patients of POAG who underwent HFDS were included. Patients were evaluated preoperatively, at 3 months postoperative and 6 months postoperative. The following parameters were assessed at the above 3 visits: IOP, superior and inferior RNFL thickness as measured on Optovue OCT, mean deviation (MD) and visual field index (VFI) as recorded by Humphrey 24-2 preimetry, and number of antiglaucoma drugs needed to maintain target IOP.


Mean± SD IOP at pre, post 3 and 6 months was 20.17±4.99, 17.00±7.19 and 16.14±4.89 mmHg respectively. Mean± SD MD at pre, post 3 and 6 months was -8.05± 9.30, -10.94±8.75 and -11.31±9.54 dB respectively. The mean± SD VFI at pre, post 3 and 6 months was 77.11±26.87, 73.25±29.45 and 71.55±31.88 respectively.The median (IQR) number of medication at pre, post 3 and 6 months were 1(0. 5, 2), 0(0,1) and 0(0,0) respectively. Mean superior/inferior RNFL thickness at pre, post 3 and 6 months was 85.54 / 81.35, 79.22 / 76.64 and 74.17 / 71.06 respectively.


There was no statistically significant difference in the RNFL thickness on OCT, and in MD and VFI on perimetry among the 3 visits. However, there was a statistically significant reduction in IOP between the prop and 3 month post op visit, and no significant difference in IOP between the 3 and 6 month post op visits. There was significant reduction in number of drugs required post surgery at 3 months, however no change was noted between 3 and 6 months. Thus, HFDS proved to be an effective surgery for reducing IOP and drug dependency in POAG patients.

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