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Long-term results after trabeculectomy combined with mitomycin C and Ologen-implant

Poster Details

First Author: S.Fili GERMANY

Co Author(s):    I. Vastardis   S. Seddig   Z. Gatsioufas   M. Kohlhaas           

Abstract Details


The Ologen-implant consists of a biodegradable collagen and glycosaminoglycan and is intended to avoid postoperative bleb scarring or encapsulation.


Clinic of Ophthalmology, St.-Johannes-Hospital, Dortmund, Germany


In a retrospective clinical study, 806 patients with advanced glaucoma were treated with trabeculectomy combined with mitomycin C 0,02% and ologen implant. The follow-up time of the study was 8 years.


A long-term reduction of the intraocular pressure below 16 mmHg was achieved in 92.6% of the patients without glaucoma eye drops in the long-term observation period. The rate of complications was very low during the postoperative period and additional surgical procedures for overfiltration with subsequent choroidal detachment were seen in 6.8% of the patients. A failure of the combined operation with phacoemulsification and implantation of an intraocular lens resulted in revision of the bleb or the application of compressive sutures in 3.35% of patients within 8 years.


The Ologen- implant was introduced in glaucoma surgery in order to increase the effectiveness of trabeculectomy and to reduce the complications. Trabeculectomy combined with mitomycin C 0,02% and an Ologen-implant provides a satisfactory filtering effect with the least undesirable effects of postoperative fibrosis.

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