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Accelerated corneal collagen cross-linking in progressive keratoconus: long-term results

Poster Details

First Author: M.Taskapili TURKEY

Co Author(s):    Y. Yildirim   B. Kepez Yildiz   A. Agca              

Abstract Details


To evaluate the long-term visual, refractive, and topographic outcomes of accelerated corneal collagen cross-linking (A-CXL) in the management progressive keratoconus.


Beyoglu Eye Training and Research Hospital, University of Health Science,Istanbul,TURKEY


Five hundred fifty six eyes of 342 patients with progressive keratoconus data were retrospectively reviewed. One hundred seventy eight eyes of 98 patients who intended accelerated (18 mW/cm(2), 365-nm ultraviolet-A light, 5 minutes) collagen crosslinking (CXL) included this study. Main outcome measures were change in keratometry, refractive status, uncorrected visual acuity (UCVA), and best-corrected visual acuity (BCVA) in five years follow up.


The mean age of all patients (48 women and 50 men) was 20.62 ± 5.6 years (range: 17 to 27 years). UDVA improved from 0.6 ± 0.4 to 0.56 ± 0.3 logMAR (P = .07) and CDVA improved from 0.52 ± 0.3 to 0.50 ± 0.29 logMAR (P = .06) at the postoperative five years visit. At the last follow-up visit, apex keratometry decreased from 58.60 ± 7.65 to 57.92 ± 6.42 D (P = .060) from baseline.


The findings of this study revealed that A-CXL treatment effective and safe option in patients with progressive keratoconus in long term follow up.

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