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Comparison of corneal biomechanical properties in post-SMILE, post-LASEK, and keratoconic eyes

Poster Details

First Author: Y.Shen CHINA

Co Author(s):    J. Shang   X. Zhou   J. Zhao   Y. Zhao   L. Zeng   X. Zhou     

Abstract Details


The purpose of this study is to investigate the corneal biomechanical properties in post-SMILE, post-LASEK and keratoconic eyes.


Eye and ENT Hospital of Fudan University, Shanghai, China; The Key Lab of Myopia, Ministry of Health, China


Eighteen eyes of 18 keratoconus patients (KC group), 18 eyes of 18 participants after SMILE (SMILE group) and 18 eyes of 18 participants after LASEK (LASEK group) with matching central corneal thickness (within±5µm) were examined. Corneal biomechanical properties were assessed using a corvis scheimpflug technology tonometer (Corvis ST). Mixed linear model analysis with Bonferroni-adjusted post hoc comparisons was performed to assess the differences in corneal biomechanical parameters between groups. The cut-off P value was 0.05.


Significant differences in the values of stiffness parameter applanation time 1 (SP-A1), applanation velocity time 1 (AV1) and interated radius (IR) were detected among groups (All P values ≤0.001). SP-A1 value of the KC group was the lowest when compared with the SMILE and LASEK (post hoc P values<0.01) groups. The AV1 value of the KC group was the highest when compared with the values of SMILE and LASEK groups (both post hoc P values <0.001). The IR value of the KC group was lower than the values of SMILE (post hoc P=0.039) and LASEK (post hoc P=0.001) groups.


The corneas of the keratoconic eyes may be the softest when compared with the normal ones after SMILE or LASEK. SP-A1, AV1 and IR may be helpful in assessing the corneal biomechanical properties of the corneas after corneal refractive surgery and keratoconus. The relations between these parameters should be dis¬cussed in further studies.

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