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Vienna 2018 Delegate Registration Programme Exhibition Virtual Exhibition Satellites 2018 Survey


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Prevention and management of Descemet's membrane endothelial keratoplasty (DMEK) complications

Poster Details

First Author: D.Santander-Garcia SPAIN

Co Author(s):    R. Quilendrino   M. Rodriguez-Calvo de Mora   K. Van Dijk   I. Dapena   L. Baydoun   G. Melles     

Abstract Details


To describe Descemet membrane endothelial keratoplasty (DMEK) complications and strategies for their prevention and management.


The Netherlands Institute for Innovative Ocular Surgery / Tertiary referral center.


Five hundred consecutive eyes DMEK of 393 patients were reviewed in this retrospective study for intraoperative and postoperative complications up to 2 years and for the corresponding management.


Intraoperative challenges (difficult graft unfolding/positioning, high vitreous pressure, iris root hemorrhage, Descemet membrane remnants) were encountered in 81 eyes (16.2%). Visually significant graft detachment was the main postoperative complication (34 eyes, 6.8%). Graft failure occurred in 8 eyes (1.6%). Other postoperative complications were increase of intraocular pressure/decompensated glaucoma in 48 eyes (9.6%), significant cataract in 11 out of 124 phakic eyes (8.9%), allograft rejection in 7 eyes (1.4%), cystoid macular edema in 5 eyes (1.0%), microbial keratitis in 2 eyes (0.4%) and retinal detachment in 1 eye (0.2%). Different strategies for prevention and management of these complications have been identified.


DMEK shows acceptable rates of complications up to 2 years after surgery which can be managed successfully. Anticipation of potential challenges and difficulties may aid in modifying intraoperative strategies for predisposed eyes. This knowledge may further minimize complications, in particular when performing DMEK for an extended spectrum of corneal endothelial disorders.

Financial Disclosure:

receives consulting fees, retainer, or contract payments from a company producing, developing or supplying the product or procedure presented

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