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Bilateral pseudo-buphthalmos in type II Peters anomaly

Poster Details

First Author: L.Mattioli ITALY

Co Author(s):    G. Giannaccare   M. Busin                 

Abstract Details


To report the clinical features of a challenging case of bilateral congenital corneal opacity mimicking buphthalmos


Ospedali Privati Forlì, Department of Ophthalmology, Forlì, Italy


A bilateral corneal opacity along with a clinical aspect of buphthalmos were present since birth in an otherwise healthy 4-month-old boy. The mother denied infection/medication history in pregnancy, and no familial predisposition to any ocular disease was declared. Upon presentation, there was no evidence of tearing, blepharospasm, or photophobia. The child underwent penetrating keratoplasty in both eyes in 2 separate sessions. During surgery, intraocular pressure (IOP) measurement, A and B-scan ultrasonography and fundus examination were performed. Histopathological assessment with Hematoxylin-Eosin staining of both the excised host corneal buttons was done to characterize the pathologic features of the cornea sections.


Surgeries was uneventful; IOP:19 in OD, 21 in OS. The A-scan ultrasonography showed an axial length of 18.71 mm OD, 18.78 mm OS . The B-scan ultrasonography revealed no masses, vitreous debris, or retinal detachment. The anterior segment structures were normal except for the presence of central adhesion of the lens to posterior corneal surface in OD with no conjunctival congestion. Fundus examination showed normal retina and optic nerve. Histological section revealed considerable cornea thinning, fibrous tissue with proliferated collagenous fiber and fibroblast, typical defects of posterior stroma, Descemet’s membrane, endothelium in the area corresponding to the zone of opacity.


In the case presented, congenital corneal opacity secondary to type II Peters’ anomaly mimicked buphthalmos. Intraoperative IOP measurement and clinical findings along with hystopathological assessment of the buttons excised helped us to reach the proper diagnosis.

Financial Disclosure:

receives consulting fees, retainer, or contract payments from a competing company

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