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Comparison of IPL with lid-squeezing group and IPL only treatment group

Poster Details

First Author: K.Shin SOUTH KOREA

Co Author(s):    D. Lim   C. Yang   C. Moon   B. Kim   T. Chung        

Abstract Details


To evaluate the effect of IPL treatment for Meibomian gland dysfunction (MGD) and the effect of lid squeezing with IPL treatment.


Department of Ophthalmology, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea


This is a randomized prospective study. Patients (232 eyes of 116 subjects) with MGD were randomly divided into two groups. Patients in group1 received 2cycle of IPL treatment using M22®(Lumenis, Dreieich, Germany) with lid squeezing for 4 weeks; patient in group2 received IPL treatment only. Ocular Surface Disease Index(OSDI), and Meibomian gland expressibility(MGE), Meibomian gland quality(MGQ) score were collected. Lipid layer thickness measured by Keratograph ®5M(Oculus, Wetzlar, Germany). To evaluate ocular surface, we measured tear break-up time(BUT) and fluorescein corneal staining score(Oxford scale). We collected data on baseline, 4weeks. Independent t-test was utilized to prove differences between two groups.


Dry eye symptom (OSDI), Meibomian gland function (MGE, MGQ), and fluorecein corneal staining score(Oxford scale)of patients were significantly improved after the treatment (p < 0.05, respectively). There was no statistically significant difference between the two groups in Oxford scale(1.86±0.245, 1.46±0.242 p=0.241), MGE(0.33±0.068, 0.26±0.091 p=0.633), and MGQ (4.09±0.558, 4.96±0.474 p=0.465) at baseline, 4 weeks respectively. No significant adverse event occurred during study period.


IPL treatment with M22® is an effective and safe treatment for MGD. But lid squeezing had no significant additional effect on IPL treatment. But our study was performed only 2 sessions, although 4 sessions were recommended as standard. Further studies would be necessary to evaluate the effect of lid squeezing on IPL treatment.

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