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Clinical characterisation of keratoconus eyes with corneal Vogt's striae: a contralateral eye study

Poster Details

First Author: S.Mosavi IRAN

Co Author(s):    F. Askarizadeh   M. Sedaghat   F. Narooie-Noori              

Abstract Details


One of the typical biomicroscopic signs of keratoconus is the Vogt’s striae, which can be unilateral or bilateral. The aim of this study was to assess and compare clinical characteristics of bilateral keratoconus patients with unilateral Vogt’s striae.


Vision Health Research Center


In this contralateral eye study, clinical characteristics were evaluated in patients with bilateral keratoconus whose corneas had definite slit-lamp biomicroscopic evidence of unilateral Vogt’s striae. All the cases underwent a comprehensive ophthalmic examination, including uncorrected and corrected distance visual acuity, manifest and cycloplegic refraction, slit-lamp biomicroscopy, Scheimpflug-based tomography,and placido-based topography. Furthermore, refractive error components were converted to vectorial notation for power vector analysis. Finally, the outcomes were compared between keratoconus eyes with and without Vogt’s striae using the paired-sample t-test and Wilcoxon signed rank test.


Fifty patients aged 20 to 38 years (27.43±5.46) were recruited in this study. The results showed a significant difference in uncorrected and corrected distance visual acuity, manifest and cycloplegic refraction , central corneal thickness, anterior chamber depth, and corneal curvature (keratometry readings) between keratoconus eyes (all P<0.05), except for J45(P=0.518 in manifest refraction and P=0.574 in cycloplegic refraction). Comparison of cycloplegic and manifest refraction in both study groups showed significant differences in the sphere and spherical equivalent (all P < 0.001), but no significant difference was found in cylinder, J0, and J45 inside the study groups (all P > 0.05).


The keratoconus eyes with Vogt’s striae had worse clinical conditions including Visual acuity, refraction, topography, and tomography than those without Vogt’s striae. The findings appear to propose that in clinical practice, when the clinical characteristics of keratoconus eyes are evaluated, attention should be paid to the presence of Vogt’s striae in the cornea.

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