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Impact of Incobotulinum toxin-A and Botulinum toxin-A on corneal curvature and astigmatism in patients with blepharospasm

Poster Details

First Author: R.Ivekovic CROATIA

Co Author(s):    B. Mihaljevic   O. Zrinscak   Z. Vatavuk              

Abstract Details


To evaluate impact of blepharospasm on corneal curvature before and after aplication Incobotulinum toxin-A (Xeomin) and Botulinum toxin-A (Botox).


University Department of Ophthalmology University Hospital Center Sestre milosrdnice, Vinogradska 29, Zagreb, Croatia


Patients with unilateral and bilateral blepharospas were evaluated. Corneal curvature and astigmatism were obtained with Scheimpflug (Pentacam) system and Auto keratometer before and after 2 weeks and 2, 3 and 4 months.


The study evaluated 12 patients, 7 with unilateral and 5 with bilateral blepharospasm, 3 males and 9 females. Six patients were treated with Incobotulinum toxin-A (Xeomin) and six patients with Botulinum toxin-A (Botox). A significant decrease in steep K and astigmatism were observed 2 and 3 months after treatment.


After tretment of blepharospasm with „Botox“ and „Xeomin“ results revealed a temporary reduction in corneal curvature.

Financial Disclosure:


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