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Interest of corneal fluorescein angiography in corneal neovascularization treatment

Poster Details

First Author: I.Hajji MOROCCO

Co Author(s):    S. Belaghmaidi   M. Baali   A. Moutaouakil              

Abstract Details


The aim of our study is to illustrate the interest of corneal fluorescein angiography to characterize cortico resistant corneal neovascularization, to differentiate mature and immature, afferent and efferent vessels.


department of ophthalmology, ARRAZI hospital, university hospital mohamed VI medical school, CADI AYYAD university, Marrakesh, Morocco


Our study was retrospective. It concerns 16 patients followed in our department on a period of 18 months (between the 1st of January 2016 and the 30th of June 2017). All our patients presented corneal neovascularization unresponsive to a 6 weeks corticosteroid treatment. All our patients underwent fluorescein angiography before complementary treatment. The images were taken every 5 seconds during 3 minutes then two images were taken at 5 and 10 min.


Mean age was 32 years old and men represented 62% of our patients. The etiology of neovascularization was herpetic keratitis in 5 cases, bacterial keratitis in 5 cases, post traumatic opacification on 4 cases. After 6 to 8 weeks corticosteroid treatment, fluorescein angiography was conducted in all non- responders patients. Fluorescein angiography allowed us to distinguish afferent vessels in 7 cases that allowed us to treat them with selective fine needle diathermy. Apical diffusion of fluorescein allowed to judge the immaturity of the vessel and conducted to practice stromal injections of anti-vegf in 6 cases.


Treatment of corneal neovascularization is currently non consensual. Anti-VEGF injections are used for immature vessels, they have no effect on mature vessels. Fine needle diathermy seems to be efficient but its effects are not predictable; it is preferable to treat selectively the afferent vessels only. Fluorescein angiography could be an interesting way to distinguish mature from immature, and afferent from efferent vessels. Despite its difficulty of realization, fluorescein angiography can be an important tool to guide corneal neovascularization treatment.

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