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When Cogan strikes twice

Poster Details

First Author: A.Cantemir ROMANIA

Co Author(s):    A. Alexa   R. Ciuntu   C. Danielescu              

Abstract Details


We report a case of 30 -year-old woman who underwent PTK for recurent erosions secondary to Cogan dystrophy and one month postoperatively was diagnosed with Cogan syndrome.


Oftaprof Clinic, Iasi, Romania


Patients with corneal map-dot-fingerprint dystrophy suffer typically from recurrent corneal erosion, disturbed vision, or both. For corneal map-dot-fingerprint dystrophy, PTK using an excimer laser is considered an effective treatment modality to achieve a durable epithelial closure, to prevent recurrent corneal erosions, and to increase visual acuity in most patients. Cogan's syndrome is a rare presumed autoimmune disorder characterized by nonsyphilitic interstitial keratitis and progressive audiovestibular symptoms.In the typical presentation of Cogan's syndrome, ocular and audiovestibular signs and symptoms usually appear alone and are bilateral.


We report a case of 30 -year-old woman who underwent PTK for recurent erosions secondary to Cogan dystrophy. The postoperative period was unremarcable, with complete reepithelization at 6 days. Two weeks postoperatively the patient complained of decreased visual acuity, redness and photophobia. Slit-lamp examination revealed large epithelial defects and peripheral corneal opacification in both eyes. Two more weeks later the patient reported having tinnitus and hearing loss and audiometry revealed sensorineural hering loss in both ears. Tratment with systemic glucocorticoids was initiated and the ocular symptoms slowly improved but the hearing loss persisted.


The constelation of clinical findings( interstitial keratitis and sensorineural hearing loss) suggested Cogan Syndrome that probably was triggered by the excimer laser procedure.

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