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Evaluation of bilateral ocular surface and tear osmolarity in patients with unilateral herpes keratitis

Poster Details

First Author: H.Bayhan TURKEY

Co Author(s):    S. Aslan Bayhan   B. Kucuk                 

Abstract Details


In this study, it was aimed to evaluate the dry eye findings and tear osmolarities of patients with unilateral herpetic keratitis and to investigate whether these findings are present in the fellow eyes without disease


Bozok University Faculty of Medicine, Ophthalmology Department Yozgat, Turkey.


In this prospective study, 40 patients with unilateral herpetic keratitis were subdivided as eyes with keratitis (Group 1) and fellow healthy eyes (Group 2 ) and one eye of 40 control subjects were evaluated. Detailed ophthalmological examinations of the cases and tear osmolarities measured with osmolarity instrument (TearLab Corporation), tear break up time (TBUT), and Schirmer tests were recorded. All subjects underwent lower and upper lid meibography and meibomian gland loss rates were measured manually.


Osmolarity score was 307.5 ± 6.9 and 303.4 ± 7.8 in groups 1 and 2, respectively and 295.5 ± 6.3 mOsm / L in the control group (p <0.05). Schirmer test score and TBUT were 8.2 ± 3.2 mm / 5 min and 5.9 ± 2.1 sec in Group1; 10.5 ± 3.5 mm / 5 min and 8.5 ± 3.9 sec in Group 2 and 14.6 ± 2.3 mm / 5 min and 12.1 ± 2.4 sec in the control group respectively (both, p< 0.05).


Unilateral stromal herpetic keratitis leads to bilateral dry eye, with more severe keratitis in the affected eye.

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