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Refractive nanolaser phaco with premium IOLs

Poster Details

First Author: M.Dvali GEORGIA

Co Author(s):    G. Mekvabishvili   N. Sharazadishvili                 

Abstract Details


To evaluate the safety and efficacy of NanoLaser Phaco procedures in patients undergoing clear (or with initial opacities) lens exchange with premium IOLs for refractive purposes.


Tbilisi State Medical University, Eye Clinic “Akhali Mzera” Ltd, Tbilisi, Georgia


17 consecutive patients were enrolled in this prospective, single-masked study. All patients underwent cataract surgery using an Infiniti Vision System (Alcon Laboratories) and the photofragmentation hand-piece of the Cetus Nano-Laser system (A.R.C. Laser) with implantation of premium IOLs (Trifocal, EDOF, Toric, Pseudoaccommodative). All patients had standard preoperative and postoperative examinations with the addition of OCT and specular microscopy to evaluate retinal thickness, endothelial cell density (ECD) and endothelial cell size variability. All surgical procedures were performed by the same experienced surgeon (M.D.). The single ophthalmologist who performed the OCT and Specular Microscopy was blinded to the type of surgical procedure.


All surgical procedures were uneventful and spectacle independence was achieved in all cases. An in-house MatLab script was used to evaluate the presence of areas in the corregistered group map with a statistically significant differences between the OCTs prior to surgery and after 24 hours. Endothelial cell counts did not present statistically significant differences following surgery.


In cases of refractive lens exchange prompt postoperative recovery is crucially important due to patients’ high expectations and demands. This study provides preliminary evidence that Nano-Laser Phaco procedure did not induce early postoperative retinal thickness and endothelial cell count modifications. The safety profile of Nano-Laser in terms of retinal thickness changes is most likely associated with the limited local extension laser-induced shockwaves that do not reach deeper structures, such as the retina. Also, no heat is generated and the overall energy utilized is significantly lower than phacoemulsification. Nano-Laser yielded good short-term endothelial cell and retinal safety.

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