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Effect of a new dual-viscoelastic device on endothelial corneal cells and intraocular pressure in cataract surgery: a comparative study

Poster Details

First Author: G.Monaco ITALY

Co Author(s):    A. Scialdone   M. Gari                 

Abstract Details


To compare the effect on clinical performance and safety in cataract surgery of two dual ophthalmic viscosurgical devices (OVD), each combining dispersive with cohesive properties but having different component concentration.


Fatebenefratelli e Oftalmico Hospital, Milan, Italy.


A total of 100 eyes of 115 patients were randomly and equally assigned to receive OVD 1 (Group 1 - ViscoPack14) or OVD 2 (Group 2 - Duovisc) during a phacoemulsification and intraocular lens implantation (IOL) in 1 eye. Postoperative examinations over 3 months included endothelial cell count (ECC), intraocular pressure (IOP), central corneal thickness (CCT), intraocular inflammation, and corrected distance visual acuity (CDVA).


In Group 1, the mean endothelial cell loss was -323.0 ± 65 cells/mm2. In Group 2, the mean endothelial cell loss was -163.0 ± 48 cells/mm2. There was no statistically difference in the mean ECC between the 2 groups. However, Group 1 showed a postoperative ECC that was statistically significant lower than the baseline values (P=0.00). At 3 hours, the incidence of IOP spikes was 0% and 5% in the OVD 1 and the OVD 2 groups. There were intergroup differences in postoperative IOP values, the Group 2 showed significantly higher values at any of the follow-up visits (P<0.05).


Both OVDs have similar clinical performance and safety profile in uneventful cataract surgery. Viscopack14 showed more endothelial cell density reduction, Duovisc more incidences of IOP spikes, and it might be considered during cataract surgery especially in patients with cornea guttata and glaucoma.

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