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Effective intracameral mydriatic treatment for tropicamide allergic blepharoconjunctivitis patients for cataract surgeries

Poster Details

First Author: N.Chiba JAPAN

Co Author(s):    H. Matsushima   S. Ito   T. Senoo              

Abstract Details


Tropicamide Phenylephrine hydrochloride eye drops (TP, Santen) are frequently used as a preoperative mydriatic for cataract surgeries. On the other hand, allergic contact dermatitis and blepharoconjunctivitis (BP) are reported as a side effect. This BP is not frequent; however, it is trouble in dealing with it. In this study, intracameral administration of diluted TP solution were performed to TP allergic patients.


Department of Ophthalmology, Dokkyo Medical University, Tochigi, Japan.


Five TP allergic patients (3 male and 2 female) were joined this study. After informed consent, the patients were disinfected and draped without TP eye drops. After ophthalmic anesthesia and corneal incision, 3.3% TP and BSS plus solution were administered into the anterior chamber at the start of cataract surgeries. After the pupil mydriasis, phacoemulcification and intraocular lens insertion were performed. The grades of BP were classified as grade 0-2, and visual acuity, intraocular pressure, corneal endothelium reduction rate, and intracameral flare concentration were observed after surgery.


There were no BP before and after surgeries in all 5 cases, and the grade of BP was 0. Corneal endothelium cell reduction rate was 6.03 ± 15% on average and intracameral flare concentration was 11 ± 1.2 photon counts/msec. There were no statistically significance with usual cataract surgeries.


The intracameral diluted TP administration is safe and effective to perfume cataract surgery for tropicmide allergic blepharoconjunctivitis patients.

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