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Wide-field corneal epithelial thickness profile by optical coherence tomography in normal-eye population

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Session Details

Session Title: Anterior Segment Imaging I

Session Date/Time: Monday 24/09/2018 | 16:30-18:00

Paper Time: 17:39

Venue: Room A4

First Author: : B.Kaluzny POLAND

Co Author(s): :    M. Kaszuba-Modrzejewska   K. Retkowska   S. Hinc   P. Mlyniuk   J. Makowski   I. Zgorska     

Abstract Details


Wide-field corneal epithelial thickness (CET) mapping is a recently introduced feature to clinically available spectral-domain optical coherence tomography (Sd OCT) system. The purpose of the study is to describe the values and distribution of CET in a normal-eye Central European population, and to explore factors associated with CET profile.


Division of Ophthalmology and Optometry, Department of Ophthalmology, Collegium Medicum, Nicolaus Copernicus University, Bydgoszcz, Poland


This retrospective, cross-sectional, observational study comprised 760 normal eyes of 380 adult individuals (194 women, 186 men). All eyes underwent routine ophthalmic examination. Corneal tomography, optical biometry and anterior segment Sd OCT including wide-field (9-mm diameter) CET mapping was performed.


In the study population, aged 47.83 ± 18.99 years, mean central CET was 54.34±3.43 µm. Within the rings 2-5, 5-7 and 7-9 mm from the center mean CET were 53.64±3.94, 52,57±4.11 and 51.44±5.23 µm, respectively. In the sectors 2-5, 5-7 and 7-9 mm superior to the center mean CET was 52.06±3.94, 50.07±4.11 and 47.47±5.23 µm, whereas inferior to the center 55.11±3.61, 54.55±3.54 and 53.01±4.26 µm, respectively. CET was also thicker in the nasal than in the temporal side. A thicker central CET was significantly correlated with male gender, older age but not with refractive error, corneal curvature or axial length.


The study provides normal-eye distribution patterns of CET in a Central European population within central 9-mm diameter zone. CET is getting thinner from the center to the periphery of the examined zone and the differences in CET between superior and inferior sectors are more pronounced peripherally. Thicker CET is correlated with male gender and older age.

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