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Vienna 2018 Delegate Registration Programme Exhibition Virtual Exhibition Satellites 2018 Survey


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Infectious keratitis after laser vision correction: incidence and risk factors

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Session Details

Session Title: SMILE vs PRK, Ocular Surface Disease

Session Date/Time: Monday 24/09/2018 | 08:00-10:30

Paper Time: 10:04

Venue: Room A3, Podium 3

First Author: : D.Teenan UK

Co Author(s): :    S. Hannan                    

Abstract Details


To describe the incidence and risk factors associated with microbial keratitis in a large population of laser vision correction (LVC) patients.


Optical Express, Glasgow, UK


Records were searched to identify all cases of presumed microbial keratitis after LVC between January 1, 2008, and April 1, 2015. Consecutive patients having primary or enhancement LVC during that time served as controls. Data on preoperative age, sex, refraction, procedure, and surgery specifics were collected. A multivariate Cox proportional hazards model was used, and hazard ratios were calculated.


Definite or probable microbial keratitis occurred in 26 of 564 165 eyes after laser in situ keratomileusis (LASIK) and in 11 of 81 792 eyes after photorefractive keratectomy (PRK) during the study period, for an overall incidence of 0.0046% (1 case per 21 697 procedures) after LASIK and 0.0013% (1 case per 7434 procedures) after PRK. A multivariate analysis found that those having PRK had a significantly higher incidence of microbial keratitis than those having LASIK (hazard ratio, 2.92; 95% confidence interval, 1.42-6.00; P = .004). No other analyzed factors were significant.


Although the incidence of infectious keratitis was higher after PRK, the overall risk after any LVC procedure was very low.

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