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Vienna 2018 Delegate Registration Programme Exhibition Virtual Exhibition Satellites 2018 Survey


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FS-LASIK vs Trans-PRK for the correction of high grade astigmatism (≥2.0D cylinder)

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Session Details

Session Title: SMILE vs PRK, Ocular Surface Disease

Session Date/Time: Monday 24/09/2018 | 08:00-10:30

Paper Time: 08:12

Venue: Room A3, Podium 3

First Author: : I.Bahar ISRAEL

Co Author(s): :    A. Gershoni   I. Vainer   E. Livny              

Abstract Details


To examine and compare the safety, efficacy predictability and clinical outcomes of Femtosecond laser assisted in situ keratomileusis (FS-LASIK) and Trans epithelial photorefractive keratectomy (Trans-PRK) procedures performed for the correction of high astigmatism (≥2.0D cylinder).


Assuta Optic, Assuta Medical Center, Tel-Aviv, Israel.


A Retrospective cohort study was performed. The study reviewed medical files of patients who underwent Trans-PRK surgery and FS-LASIK surgery for the correction of high astigmatism (≥2.0D) between the years 2013-2014. The FS-LASIK group comprised of 93 eyes, and 186 eyes were examined in the Trans-PRK group. The pre-operative Spherical equivalent (SE) for FS-LASIK was -3.65±2.05 and -4.99±2.46 for Trans-PRK (p<0.001), and the pre-operative cylinder was -2.76±0.79 and -2.72±0.84, respectively (p=0.732).


There were no statistically significant differences between FS-LASIK and Trans-PRK in post-operative SE (-0.1±0.7 and -0.11±0.7, respectively, p=0.958) and residual cylinder (-0.79±0.54 and -0.82±0.63, respectively, p=0.685). However, Trans-PRK was associated with worse outcomes compared to FS-LASIK in both the safety (0.89±0.21 and 1.03±0.17, respectively, p<0.0001) and efficacy (0.86±0.22 and 1.00±0.18, respectively, p<0.0001) indices. These results remained significant in multivariate analysis after correcting for age, gender, preoperative refractive error and pachymetry.


Although both procedures achieved a desirable post-operative SE, FS-LASIK showed vast superiority over Trans-PRK for the correction of high-grade astigmatism (≥2.0D cylinder).

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