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Vienna 2018 Delegate Registration Programme Exhibition Virtual Exhibition Satellites 2018 Survey


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Long-term survival analysis of iris-fixated phakic intraocular lenses

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Session Details

Session Title: Phakic IOLs

Session Date/Time: Sunday 23/09/2018 | 08:00-10:00

Paper Time: 08:06

Venue: Room A3, Podium 1

First Author: : S.Jonker THE NETHERLANDS

Co Author(s): :    A. Van Averbeke   T. Berendschot   I. Saelens   N. Bauer   R. Nuijts        

Abstract Details


To determine the rates of explantation and survival time of several different types of phakic intraocular lenses (pIOLs), and to assess risk factors for pIOL explantation.


Academic Center for Refractive Surgery, University Eye Clinic Maastricht, Maastricht University Medical Center, Maastricht, The The Netherlands.


Survival analyses were performed using data from patients implanted with six types of iris-fixated pIOLs (Artiflex, Artiflex Toric, Artisan Toric, Artisan Hyperopia, Artisan Myopia [Ophtec, Groningen, the The Netherlands]), from 1998 until November 2016. Thousand-thirty-nine eyes with a mean preoperative age of 40.1±11.0 were included. Multiple measurements were performed preoperatively, and in succession 1 day, 1 week, 1, 3, 6 and 12 months postoperatively, followed by annual visits after completing the first year of follow-up. Kaplan Meier and multivariate Cox regression analyses were performed to report survival time and asses risk factors for pIOL explantation.


The overall rate of explantation in this study was 12% (n = 120). We report an estimated median survival (i.e. time until 50% of pIOLs is explanted) of 183 months (15.3 years). Patients with a higher preoperative age (HR 1.07/year, 95% CI=1.04–1.09, p < 0.001), greater axial length (HR 1.10/mm, 95% CI = 1.02–1.18, p = 0.009), or smaller anterior chamber depth (HR 4.47/mm, 95% CI=2.43–8.22, p < 0.001) are likely to have a shorter survival. Analyses describing risk factors for explantation due to cataract or endothelial cell loss, and differences between lens types, will be presented.


It is estimated that it will take 15.3 years until 50% of all pIOLs are explanted. Higher age at implant, greater axial length and smaller anterior chamber depth significantly increase the chance of a shorter survival in eyes implanted with iris-fixated pIOLs.

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