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Pseudoexfoliation in intraocular lens

Poster Details

First Author: S.Lozano Ruiz SPAIN

Co Author(s):    C. Gomez   L. Salcedo Garrote   S. Nebro Cobos              

Abstract Details


The pseudoexfoliation syndrome is a generalized disorder of the extracellular matrix, related to age, associated with excessive production and accumulation of an extracellular fibrillar material (PEX material), inside and outside the eye. At the ocular level, pseudoexfoliation is associated with glaucoma, a cataract with subluxation of the lens and obstruction of the central vein of the retina. Eyes with PEX have a higher frequency of complications during surgery due to zonular weakness and poor pupillary dilation.


An 83-year-old woman, who underwent surgery for cataracts in 2012, attended to a medical examination due to a decrease in visual acuity caused by an opacification of the posterior capsule of the lens, presenting Pseudoexfoliative material on the anterior surface of the intraocular lens.


Her right eye visual acuity was negligible and she had 0.3 in the left eye. A Yag capsulotomy was performed with evaluation of posterior visual acuity in OD of 0.8 and OI 0.7 with perfect capsulotomy yag and pseudoexfoliative material on the anterior Surface of the intraocular lens . The intraocular pressure was 10 in both eyes and the funduscopy presented no pathological findings.


The physiopathology is associated with high production of microfibrillar components that make up a matrix resulting from excessive production or insufficient elimination. The curious thing about this case is the finding of Pseudoexfoliative material on the anterior surface of the intraocular lens, since its most common location is at the pupillary border, and on the anterior surface of the lens capsule.


There is no prevention or specific treatment to avoid pseudoexfoliation, so it is important to take into account this syndrome on account of associated ocular diseases and surgical complications. It is essential to carry out a rigorous preoperative study to personalize the surgery, trying to stabilize the capsular bag as much as possible, and carry it out early, as everything gets worse with age and time. It is also important to perform a thorough post-surgical control.

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