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Palpebral chronic lupus erythematosus: about three cases

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First Author: K.Bouirig MOROCCO

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Abstract Details


The purpose of this work was to illustrate the clinico-pathological and therapeutic features of lupus palpebral involvement.


K. Bouirig.


We report 3 cases of eyelid involvement in lupus disease. In two cases, this was the only localization of the disease.


We report the cases of one man and two women, with an average age of 39 years old,  They presented with erythematous and squamous plaques of the face and scalp with chronic cheilitis in two of them. Palpebral erythematous and squamous plaques were also noticed in all of them. Ophthalmological examination didn’t reveal any ocular involvement. Histological study of the palpebral  of the three patients revealed interface dermatitis with a positive lupic band in direct immunofluoresence. A treatment based on hydroxychloroquine associated with photoprotection was established with a good improvement after 3 months follow-up.


Palpebral involvement of lupus erythematosus is an uncommon condition. It is often associated with others lesions on the cephalic area. However, it can be isolated leading to error and delayed diagnosis. The most frequent palpebral manifestations of lupus erythematous are erythematous plaques sometimes covered with scales or telangiectasia, most often sitting on the lower eyelid. Associated ocular involvement, particularly corneoconjunctivitis, is possible imposing an ophthalmological examination. Differential diagnoses include the other causes of blepharitis. Treatment is based on synthetic antimalarials and photoprotection and sometimes topical corticosteroids or thalidomide.

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