Official ESCRS | European Society of Cataract & Refractive Surgeons


Efficacy of a hydroxypropyl guar and hyaluronic acid ophthalmic solution on ocular discomfort after cataract surgery

Search Title by author or title

Session Details

Session Title: Cataract Surgery: Complications & Management

Session Date/Time: Tuesday 17/09/2019 | 14:00-16:00

Paper Time: 15:34

Venue: Free Paper Forum: Podium 1

First Author: : E.Favuzza ITALY

Co Author(s): :    M. Cennamo   A. Miele   R. Mencucci                       

Abstract Details


To evaluate the effects of a hydroxypropyl guar (HPG) and hyaluronic acid (HA) ophthalmic solution on post-cataract surgery ocular discomfort.


Multicenter study, Italy


350 patients not affected by dry-eye syndrome, scheduled for unilateral cataract surgery were enrolled. All patients followed the same antibiotic and anti-inflammatory postoperative topical regimen. They were randomly divided in three groups: 1) control group: no additional artificial tears; 2) study group A: HPG/HA solution 3 times/day in the preoperative week and for two postoperative months; 3) study group B: HPG/HA only for two postoperative months. At the preoperative visit and at 1,4 and 8 postoperative weeks SPEED (Standard Patient Evaluation of Eye Dryness) questionnaire score, tear Break-up Time (BUT) and fluorescein staining score (Oxford scale) were evaluated.


At week 4 and week 8 postoperative visits, SPEED score was significantly lower in the two study groups than in the control group (p<0.05), and BUT was significantly higher in study group A and study group B in comparison with controls (p<0.05). At these visits BUT was higher in the study group A than in the study group B, even if without statistical significance.


Hydroxypropyl guar and hyaluronic acid ophthalmic solution was effective in reduction of post cataract surgery ocular discomfort, particularly if administered also in the preoperative period.

Financial Disclosure:


Back to previous