Official ESCRS | European Society of Cataract & Refractive Surgeons


A multicentre survey for the prevalence of dry eye disease in Chinese refractive surgery candidates

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Session Details

Session Title: Small Incision Lenticule Extraction II

Session Date/Time: Monday 16/09/2019 | 16:30-18:00

Paper Time: 16:30

Venue: Free Paper Forum: Podium 3

First Author: : M.Li CHINA

Co Author(s): :    X. Zhou                             

Abstract Details


Dry eye is a common complaint among patients who have undergone refractive surgeries.It has been reported that patients who develop dry eye after refractive surgery also have elevated risks of developing subsequent refractive regression and ocular surface damage.Thus, it is important for corneal refractive surgeons to find out those patients with severe dry eye before surgeries to offer more careful perioperative management. The purpose of this study was to determine the prevalence of dry eye in a corneal refractive surgery population in China, as well as identify the effect of contact lens wear on dry eye.


Patients enrolled in this study were consecutive refractive candidates who received preoperative evaluations in 1 of the 13 hospital or eye centers in China.


Refractive surgical candidates visiting 13 pre-selected eye hospitals and centers in China were recruited after informed consent. Information of contact lens (CL) wear history were collected from every patient as risk factor of dry eye. Within 3 months before refractive procedures, diagnostic examinations for dry eyes, including subjective symptoms inquiry, tear film breakup time (TBUT), corneal fluorescence staining and Schirmer I tests (SIT), were performed for diagnosis and subgroup analysis of dry eye.


Among all 1849 recruited subjects, total of 766 were diagnosed dry eye disease (a prevalence of 41.4%); 44.9% of subjects have a positive history of contact lens wear. The mean TBUT and SIT values was 7.3±3.7s and 15.2±8.8mm, respectively. The total prevalence of corneal fluorescence staining was 22.8% (422/1849). Contact lens wearers were observed to have higher prevalence of dry eye than non-contact lens wearers (54.1% vs 35.2%, OR=2.17, 95%CI: 1.77-2.65).


In this study, high proportion of refractive surgery candidates have a history of contact-lens wearing and dry eye. Contact lens wearers were observed to have higher prevalence of dry eye than non-contact lens wearers. Attentions should be paid to preoperative dry eye in refractive surgery candidates.

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