Official ESCRS | European Society of Cataract & Refractive Surgeons


Topography-modified refraction (TMR): partial to total adjustment of treated cylinder amount and axis provided by topography data measured vs using the standard clinical refraction in myopic topography-guided LASIK

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Session Details

Session Title: LASIK & PRK II

Session Date/Time: Monday 16/09/2019 | 14:00-16:00

Paper Time: 14:36

Venue: Free Paper Forum: Podium 3

First Author: : F.Tzani GREECE

Co Author(s): :    A. Kanellopoulos                             

Abstract Details


The purpose of this study is to compare the outcomes of 50% and 100% Topography-Modified Refraction (TMR) to each other and to the standard clinical refraction in patients having myopic topography-guided LASIK for myopia.

Setting: Clinical and Research Eye Institute, Athens, Greece


In this contralateral, prospective randomized consecutive case series, 240 eyes (120 patients) have undergone myopic (with corresponding astigmatism) topography-guided LASIK. One eye of each patient (Group-A) was treated with the standard clinical refraction (sphere, cylinder and axis), while the contralateral eye with: either 50% Topography-modified refraction (TMR) (group-B); or 100% Topography-modified refraction (TMR) (group-C); The 3 months peri-operative visual performance and refractive data were compared for all three groups.


Mean pre-operative refractive error was:−4.5D of myopia and −1.75D of astigmatism. In average numbers at 3 months:UDVA: 6.25% of groupA,0% of groupB and 0% of groupC was ≦20/20; 25%, 28.57% and 29.34% was 20/20; 68.75%, 71.42% and 70.66% was >20/20 respectively; 1line of vision gained:56.25%, 42.85% and 66.67%; 2 or more lines of vision gained was 12.5%, 28.56% and 33.33% also respectively. In-groupA, 50% of eyes had less than 0.25 diopters of residual refractive astigmatism, 71.42% in groupB (P<.01) and to 77.76% in group C(P<.01). All values were statistically different when groupB was compared to groupC.


Topography-modified refraction (TMR) used in myopic topography-guided cases, appears superior to clinical refraction used. Complete adherence to the topography cylinder amount and axis appears to offer the best outcomes in this contralateral eye comparison.

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