Official ESCRS | European Society of Cataract & Refractive Surgeons


Multicentre prospective randomised clinical trial to evaluate the depth of focus of AT LARA 829MP, TECNIS Symfony and CT ASPHINA 409MP

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Session Details

Session Title: Extended-Depth-Of-Focus IOLs I

Session Date/Time: Sunday 15/09/2019 | 14:00-16:00

Paper Time: 14:00

Venue: Free Paper Forum: Podium 1

First Author: : E.Bertelmann GERMANY

Co Author(s): :    T. Brockmann   A. Kapp   T. Reinhard   L. Kiraly   S. Colonval   J. Nascimento              

Abstract Details


To evaluate clinical outcomes with an extended depth of focus IOL (LARA) compared to an extended-range-of-vision IOL (Symfony) and a monofocal IOL (ASPHINA).


Nine European clinics in Germany, Belgium, Portugal, Spain and Italy


Multicentric, prospective, randomised clinical study including 428 eyes of 214 patients undergoing cataract surgery with bilateral implantation of AT LARA 829MP (Carl Zeiss Meditec), TECNIS Symfony (Johnson & Johnson) or CT ASPHINA 409MP (Carl Zeiss Meditec). Postoperative examinations included assessing monocular and binocular visual acuity, subjective refraction, depth of focus, patient satisfaction and subjective quality of vision at 1 month. Defocus and visual acuity testing were performed using the electronic Freiburg Visual Acuity and Contrast Test (FrACT) and a questionnaire was used to evaluate patient satisfaction and quality of Vision.


Two-hundred-thirty-four patients were assessed for study eligibility and 200 patients completed the outcome assessment at 1 month postoperatively. Mean corrected distance visual acuity did not differ statistically significantly between groups (p>0.05). Monocular defocus curves showed the extended-depth-of-focus and extended-range-of-vision IOL had better intermediate and near performance than the monofocal IOL. The monocular depth of focus at a 0.3 logMAR threshold was statistically significantly wider with LARA compared to Symfony (p=0.0298) and ASPHINA (p=0.0002) IOL. The questionnaire results for quality of vision showed better results for the monofocal IOL especially for halo perception compared to the extended-depth-of-focus and extended-range-of-vision IOL.


The extended-depth-of-focus IOLs provided wider depth of focus compared to the extended-range-of-vision IOLs and monofocal IOLs and comparable distance visual acuity results.

Financial Disclosure:

research is funded, fully or partially, by a company producing, developing or supplying the product or procedure presented, research is funded, fully or partially, by a competing company

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