Official ESCRS | European Society of Cataract & Refractive Surgeons


Window absorption corneal cross-linking in the treatment of severe corneal ulcers: long-term follow-up

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Session Details

Session Title: Ocular Infections & Other Topics

Session Date/Time: Sunday 15/09/2019 | 08:00-10:00

Paper Time: 08:06

Venue: Free Paper Forum: Podium 4

First Author: : P.Rosetta ITALY

Co Author(s): :    F. Camesasca   E. Legrottaglie   A. Borgia   P. Vinciguerra                    

Abstract Details


We treated severe infectious corneal ulcers with antibiotic therapy and Window Absorption corneal cross-linking (CXL-WA).


Humanitas University Clinical and Research Center, Rozzano, Milan, Italy


Ten eyes with severe keratitis and corneal melting (4 Pseudomonas Aeruginosa, 2 Staph. Epidermidis, 1 coagulase-negative Staph., 1 Strept. pneumoniae, 2 Acanthamoebae) were treated with antibiogram-guided topical antibiotic therapy and CXL-WA. Minimum follow-up was one year.


Treatment healed corneal infection. OCT showed long-term increase in stromal density, tomographic stability, and no ectasia even in thinned corneas (<300μm). Demarcation line was deeper than 200 microns.


CXL-WA-mediated increase in corneal strength stabilized these severely damaged preventing more invasive approaches.

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