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Incidence and predisposing factors of anterior chamber gas bubbles during femtosecond laser flap creation using WaveLight FS 200

Poster Details

First Author: S.Ausayakhun THAILAND

Co Author(s):                        

Abstract Details


To investigate the incidence and the predisposing factors of anterior chamber (AC) gas bubbles during femtosecond laser flap creation using WaveLight FS 200 during laser in-situ keratomileusis.


Chiang Mai University (CMU) LASIK Center, Faculty of Medicine, Chaing Mai University, Chiang Mai, Thailand.


A retrospective case-control study of patients who underwent femtosecond LASIK surgery was carried out. A review of the preoperative data of the patients included patient demographics, visual acuity, manifest refraction, pupil size, keratometry, white-to-white (WTW) corneal diameter and central corneal thickness. The intraoperative data included the flap parameters (diameter, thickness, hinge position, and tunnel length), docking times, and number and size of gas bubbles. Univariate, and multivariate conditional logistic regression were used to determine the risk factors for AC gas bubbles during the use of a femtosecond laser for flap creation, using the eye as the unit of analysis.


The incidence of AC gas bubbles was 1.6% (22 in 1,378 eyes). Patients with AC bubbles had a median age of 31 years. Gas bubbles appeared preferentially in the left eye (72.7%). The median WTW diameter in the AC bubbles group was 11.5 millimeters, which is significantly different from the control group (p = 0.021). The logistic regression analysis showed that the result of the WTW minus the flap diameter and minus the hinge canal length in the AC bubbles group when compared to the control group had an odds ratio of 0.25 (95% CI; 0.08-0.82, p = 0.022)..


Development of AC gas bubbles during femtosecond laser flap creation is a not uncommon event in Asian eyes. Asian eyes typically have a small WTW diameter. The flap diameter and the canal length of the hinge, when adjusted relative to the WTW diameter, are the predisposing factors to the possibility of the AC gas bubbles occurring.

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