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Bilateral corneal perforation due to aggressive Mooren`s ulceration

Poster Details

First Author: L.Patrao Buscacio BRAZIL

Co Author(s):    E. Buscacio   M. Alves   D. Chianello   A. Lacerda   H. Caminha        

Abstract Details


To describe bilateral corneal perforation secondary to severe peripheral corneal ulceration in a male patient without ocular infection or systemic rheumatological diseases.


Hospital Federal dos Servidores dos Estado, Rio de Janeiro, RJ, Brazil


A single retrospective case report.


A 27-year-old male patient presented with bilateral peripheral corneal ulceration following a 10-month history of ocular discomfort and redness. The patient underwent extensive medical and laboratory testing to rule out an infectious or systemic cause of his corneal ulcer. Despite high-dose topical and oral corticosteroids, he presented increased pain. At that time, limbal conjunctival excision was performed in both eyes. The patient presented acutely with corneal perforation in the left eye and, shortly thereafter, with corneal perforation with iris prolapse in the right eye. He was treated with annular peripheral penetrating keratoplasty in both eyes and immunosuppression.


Mooren's ulcer is an idiopathic, painful, progressive ulceration of the peripheral cornea, that usually respond poorly to conventional therapy. In this case, despite the clinical treatment, the patient rapidly progressed into a bilateral corneal perforation. Corneal transplantation combined with immuno-suppression led to a favorable outcome.

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